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The Jean Jeener NMR Center is
equipped with two state-of-the-art spectrometers, enabling a
wide range of studies on biological macromolecules. Applications
range from the determination of protein structures at atomic
resolution, to the analysis of binding affinities of macromolecular
complexes.
The lab is part of the Structural Biology Brussels
laboratory at the Vrije Universiteit Brussel, and of the VIB Department for Molecular and Cellular
Interactions.
The center was officially opened on the 7th of May 2010. (See the scientific and official program for this event.)
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Open Position
The Jean Jeener NMR center at the Faculty of Science and Bioengineering Sciences at
the Vrije Universiteit Brussel invites applications for a (post-)doctoral project in
Bio-NMR of glycan-based interactions in infectious diseases
Provisionally starting on October 1, 2010, for the duration of 3 years.
The beginning scientist is expected to have a good theoretical background in biochemistry
and protein structure, and a profound interest in learning NMR spectroscopy for protein
and glycan structural determinations and molecular interaction studies. It involves:
- expression and purification of isotope-enriched proteins
- in-depth NMR for the study of the dynamic aspects of glycan-based binding
- microcalorimetry for thermodynamic analyses
The project is part of a bilateral agreement for translational medicinal chemistry research
between the FWO - Flanders and Quebec, Montréal, Canada, where the synthesis of
antimicrobials will take place. Linked experiments are microscopy on biofilms and
in vivo imaging, aimed at optimization of those. He/she will work in the
internationally renowned Bio-NMR research team of Prof. Nico van Nuland
and in collaboration with Dr. Julie Bouckaert.
Candidates should have applied or have the intention to apply for
(post-)doctoral grants for which they are eligible.
Your CV and a letter explaining why you like to apply have to be sent
in to each of the three contact persons below. Further information
can also be obtained from either:
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Dr. Julie Bouckaert
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Prof. Lode Wyns
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Prof. Nico van Nuland
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Structural Biology Brussels
Vrije Universiteit Brussel
Pleinlaan 2, 1050 Brussel
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Tel: +32-2-6291988
bouckaej@vub.ac.be
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Tel: +32-2-6292108
ljwyns@vub.ac.be
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Tel: +32-2-6293553
nvnuland@vub.ac.be
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